Mast Cell Activation Syndrome (MCAS) is a condition in which mast cells—immune cells that help defend the body—release excessive or inappropriate amounts of chemical mediators, like histamine, in response to triggers. Because mast cells are present throughout the body, symptoms can affect nearly every organ system, making MCAS a “great imitator” that is often misdiagnosed. The underlying causes often involve a combination of genetic, environmental, and immunological factors. Some people may have a hereditary tendency toward mast cell dysregulation, while others may develop MCAS secondary to chronic infections (like Lyme disease), mold exposure, toxins, or even stress. It can also be associated with other conditions such as Ehlers-Danlos Syndrome, POTS (Postural Orthostatic Tachycardia Syndrome), and Chronic Fatigue Syndrome. In addition to the more common symptoms of flushing, hives, and gastrointestinal issues, MCAS can cause a wide variety of other symptoms, including:

Headaches or migraines

Dizziness or lightheadedness

Shortness of breath or asthma-like symptoms

Anxiety or panic-like episodes

Nasal congestion or sneezing

Low blood pressure or episodes of near-fainting

Menstrual irregularities

Bone or joint pain

Rapid heartbeat

Brain fog

Sensitivity to foods, smells, temperature, or chemicals

Itchy or watery eyes and even anaphylaxis

Management typically involves avoiding known triggers and using medications like antihistamines and/or mast cell stabilizers to control symptoms.

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Phone: 860-677-4600 
Email: OfficeManager@NaturalHealthandHealing.net